Dermal Energizing Treatment
2 points per dollar


Reinvigorate your appearance! Based on years of research, the ingredients in CytoCell™ Dermal Energizing Treatment are designed to combat the visible signs of aging. The result is a rejuvenated complexion.

  • Peptide P-199 is formulated to reactivate and re-energize and help improve the appearance of fine lines and wrinkles.
  • Shea Butter, Vitamin E, and Soy Lipids work together to moisturize skin and provide sustained hydration.
  • An Antioxidant blend of Geranium, Lavender, and Bergamot Extracts helps soothe and calm skin.

How to Use

AM and PM. Use twice a day. Apply a thin, even layer to face and neck. Use alone or layer over a treatment serum.


Water (Aqua), Butyrospermum Parkii (Shea Butter), Glycerin, Dimethicone, Ethylhexyl Isononanoate, C4-24 Alkyl Dimethicone/Divinyldimethicone Crosspolymer/Isodecyl Isononanoate, Isohexadecane, Tridecyl Trimellitate, Pentylene Glycol, Behenyl Alcohol, Cetearyl Alcohol, Hydrogenated Lecithin, Linoleic Acid,Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Whey Protein, Cetearyl Glucoside, Linolenic Acid, 1, 2-Hexanediol, Caprylyl Glycol, Polysorbate 80, Disodium EDTA, o-Cymen-5-OL, Lavandula Angustifolia (Lavender) Oil, Lavandula Hybrida Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Pelargonium Graveolens Flower Oil, Pogostemon Cablin Oil, Polydiethyleneglycol Adipate/IPDI Copolymer, Tocopherol, Tropolone, Polypeptide-72, Citronellol, Limonene, Linalool
    • Kate Somerville's products are very consistent when it comes to fragrance, texture, and quality. This product has a pleasant fragrance that's light and not overwhelming. None of the strong chemical smell a lot of products have. It is light and smooth in texture. Spreads well on the skin and little product is needed to cover the entire facial and neck area. Another reason why I love her products is because I never have to use too much. You can tell there are no harsh dyes in this product.

      (Posted on 8/7/14) Review by Kathy
    • I use this as a moisturizer and it works well. I've just not found a big difference in skin condition after utilizing this. It may be that my skin is good enough to not have this make a big difference.

      (Posted on 8/5/14) Review by Clarissa
    • I sampled this cream and fell in love. its hydrating but not overwhelming on my sensitive skin. I will be buying a full version of this soon!

      (Posted on 8/3/14) Review by Npelaez315
    • This is my favorite face cream. It is very hydrating and it does feel 'energizing'. I love the smell, every morning I put it on it reminds me of my first Kate Somerville facial. It is expensive, but, I can't live without it now!

      (Posted on 5/10/14) Review by TRACY
    • I got a sample of this and had to buy the full version. It's great for the winter months. My skin is really sensitive and oily so at times i feel this cream might have been a little too rich for me. But overall it really improved my skin texture and felt very nice to put on.

      (Posted on 4/29/14) Review by Nadia
    • I was using Age Arrest before, but this is my new best friend! I love the smell, the feel, and how it hydrates throughout the day. My makeup goes nicely over it as well (always a perk)! It's so nice that I got my mom on it and her skin is looking amazing! Highly recommend.

      (Posted on 4/15/14) Review by ShibaInSeattle
    • One of my favorite Kate products. I need moisture but don't like anything that feels too heavy on my skin. Feels great, moisturizes yet isn't heavy - perfect! A must for my skin care routine

      (Posted on 4/5/14) Review by Michele
    • This treatment really revives the skin. It's great for the dry, winter months. It's very moisturizing and comfortable on the skin but not too heavy. It also doesn't make me break out. I've noticed that my skin is more even and less red when using this, and I also look less tired. I'd recommend it.

      (Posted on 3/18/14) Review by megan
    • Last year I received Cytocell from Sephora as a deluxe sample. Again, I was so impressed with another Kate Somerville product that after sparingly using two samples, I made the purchase. Whenever buying one of Kate's products I have to deeply consider the pros and cons since my graduate school budget does not lend itself well to making such expensive purchases. However, with nightly applications over several weeks my skin was softer, dewier, and had more elasticity. The texture is creamy yet light and airy and the fragrance is pleasant. My skin type tends toward oily and sensitive and this was not too heavy on my face nor did it cause any blemishes.

      (Posted on 3/9/14) Review by JENNIFER
    • I have found that this product addresses so many issues from dry skin to acne to minor wrinkles. It makes my skin feel very smooth. The only reason I rated it 4 our of 5 stars is I'd like to see some sort of "window" which would show when the product is running low so I can reorder and never go without!

      (Posted on 2/28/14) Review by Maureen
    • This is my Holy Grail! I've said it before on a Sephora review & it's worth repeating! The way my skin looks & feels while using Cytocell is fantastic. The packaging is brilliant, as it dispenses the exact amount I need. The smell is divine. While I wouldn't strictly use or not use a product based on scent, it is an absolute treat! I've tried to go without Cytocell in the past, only to notice my skin looking dull, flaky & dehydrated. Thank you, Kate, for a wonderful product.

      (Posted on 2/8/14) Review by Beth
    • I had first received this as a sample. I love it! Thank God, I was able to purchase this on here for the Black Friday Sale! I jumped on ordering this! This firms my face,smooths out my fine lines around my eyes! Wow! This stuff is amazing! Will not be without it!

      (Posted on 1/1/14) Review by Karen
    • I received this for Mothers Day from my daughters. It really evens out your skin and keeps the moisture level perfect. I just re-ordered because my husband has been using it,too. His skin looks good also.

      (Posted on 12/30/13) Review by Heidi
    • This cream is very hydrating and at the same time, refreshing, I get a cool "aaah" sensation on my face. The fragrance is light but there, like a spa citrusy scent, I love it but if you're sensitive be aware. It fades after a few minutes. I use the oil free cream during the day and this one at night now in the winter, I can't attest to the wrinkle reducing powers, only that it's very hydrating and soothing. I have rosacea and no redness nor breakouts, so that's a winner for me!

      (Posted on 12/23/13) Review by siverlady44
    • I love the look and feel of this product! This is my favorite cream from Kate as it relates to smell and the way it feels on my skin. The only reason I gave it four stars is because of the price. I still think it's a little pricey for what it is, especially if you want to pair it with the serum or eye cream.

      (Posted on 12/11/13) Review by Jennifer
    • I use this when my skin is feeling a little less radiant, due to vacations, weather, other products, etc. I notice a difference in the plumpness of my skin when I use this moisturizer. It has a great ability to moisturize without being heavy.

      (Posted on 12/3/13) Review by charlie
    • I would give this product more than 5 stars if I could, that's how much I love it. The first time I tried this moisturing treatment it made my skin look so healthy and youthful. I've been using this product ever since. I'm hooked and won't use anything else at night. While the directions recommend to use this every morning and night, I only use it at night because it's so expensive! I use Kate's goat milk moisturizer (another great product for dry skin) in the mornings.

      (Posted on 12/1/13) Review by dfm
    • I love this product. I actually use it for a moisturizer before I apply my makeup in the morning and use it at night after cleansing. It is definitely worth it!!!!

      (Posted on 11/28/13) Review by tiffeny
    • I can't even begin to explain the change in my skin since starting this product. It has solved so many issues (minor acne, dry skin, dark spots), that I absolutely can never go without it ever again!

      (Posted on 11/25/13) Review by Maureen
    • This product was recommended to me by the Kate Somerville Rep. She gave me a sample of it to try. Just one time use, I could fell the difference on my skin. I went back tot he Dept store counter and purchased it. I used this product for night cream, and by morning my skin feels wonderful. Since I started with Kate Somerville skin care products, people made comments on how young I look. Those comments boosted my days!

      (Posted on 11/24/13) Review by arlene
    • I received a small sample and have been using this product sparingly on my cheeks for the past month. The cream feels luxuriously light and airy with a nice light scent. I can see the improvement in the resilience and firmness of the skin after application. I also have used this on a small scar and it has reduced the appearance of the scar. Would definitely recommend.

      I reduced I star because I'm new to the product line and given the price, I have not tried her other products to see which is the most effective.

      (Posted on 11/24/13) Review by kelley
    • I've been using this for some acne scars and it's help alot. I just spot treat instead of putting it all over my face. It's a great product for discoloration and texture improvement.

      (Posted on 11/21/13) Review by Caroline
    • in a previous review i said that this moisturizer was too heavy, but it was summer and i thought maybe in winter it would be fine for daytime use. well, it's autumn and i've been using this most days (some days i use nourish daily moisturizer), and i love it! even though i have oily skin, i prefer moisturizers on the heavier side (hence my surprise that this was too heavy at the time), and this one is just right for fall/winter. not sure yet whether i will repurchase when it runs out, but for now i am really happy with it. it's helped to heal a particularly bad breakout i was having.

      (Posted on 11/6/13) Review by alex
    • By far, the BEST moisturizer EVER. I love this product. It feels light on your skin.

      (Posted on 10/28/13) Review by Nicole B
    • CytoCell Dermal Energizing Treatment is awesome!! It has transformed my skin. I've stopped looking for that "special" product.....FOUND IT!!

      (Posted on 10/28/13) Review by DANA
    • I Recently Received This As A Free Gift.I Gave It To My Mom To Try And She Loves It.She Has Tried Samples Of The Deep Tissue Repair But Likes This Better.She Has Seen Her Skin Improve With Each Use.Her Face Is Glowing.

      (Posted on 10/27/13) Review by lorraina
    • Been using it for almost two weeks, its little bit oily for me. I like the CytoCell P299 Serum more, but still a nice lotion.

      (Posted on 10/18/13) Review by JENNY
    • I received a sample of this product and I had heard good things. Perhaps a sample is not long enough to judge it by, but I didn't notice as much of a difference as I'd like. It felt nice going on the skin, and felt moisturizing, but I didn't notice as much of a "glow". It did make my skin feel soft, so it does have that going for it :)

      (Posted on 9/6/13) Review by H
    • I had a ultimate kate facial at the four seasons in maui and they recommended this product and I have used it ever since. I like to use it at night and my skin looks younger, firmer, brighter. It is a facial in a bottle! Love love love it!

      (Posted on 9/6/13) Review by Kimberely
    • This is the best moisturizer I've ever used. My skin is combination dry and oily and I'm in my early thirties and am trying to prevent wrinkles and any skin damage. Given my skin type, it has been difficult finding a moisturizer that can fit all my skin's needs. CytoCell has been a miracle. After using CytoCell and ExfoliKate for just two weeks, I was getting so many compliments on how my skin looked so clear and glowing. This is definitely the best my skin has looked in a long time and I'm so glad to have finally found a product that suits my needs.

      (Posted on 8/22/13) Review by Anni
    • I've used this product for just a week but already have seen a huge improvement in the appearance of my skin. My face is softer, glowy, and looks better than it has looked in a decade. Worth every penny.

      (Posted on 8/18/13) Review by Anna
    • My skin feels amazing when I use this product.

      (Posted on 7/23/13) Review by Jody
    • This is one of the best products I have tried from this line. While I would not call this a miracle product(I doubt if there is something like that in any case), I love how this makes my skin feel. Keep in mind that little goes a long way, I have oily skin and I did the mistake of using too much on my skin and the next morning my face was a grease ball. I love the hygienic packing as well as the smell of this product. My skin feels plumper the next morning and looks very hydrated. I use it every other day as this is an intensive moisturizer in my opinion.

      (Posted on 7/11/13) Review by Sweta
    • This may be the best moisturizer I've ever used. And I've tried everything. I have acne prone, combination skin with clogged pores. I'm also 35 and starting to see fine lines and wrinkles mixed with a few age spots. After only a few nights of using this, my skin has more clarity and is so soft! I'm never care about the packaging on products but I love the way this is dispensed. It's very hygienic and gives a perfect amount. It is expensive but what I wouldn't pay for great skin... Try it for one night and you won't be disappointed!

      (Posted on 7/7/13) Review by Amber
    • I received a sample of this and did not notice any change in my skin. Perhaps it takes longer than a few uses to see results...

      (Posted on 7/7/13) Review by Luella
    • I use this moisturizer as a treatment in the AM after my Total Vitamin followed by deep tissue, and in the PM after the restor 8 followed by the deep tissue. Keeps my skin hydrated and radiant.

      (Posted on 7/2/13) Review by Jeanne
    • i have not been using this product daily because it is a little heavy. typically, if i use it, i do so only at night as a night cream. i have oily skin and i find that this cream is simply to heavy for daytime use. part of the problem is that i ordered it at the beginning of spring; i think that i could use this as a day cream in the winter when my skin is a little dryer. because i have not been using it every day, i cannot attest to whether it provides any of the claimed longish-term benefits. i seldom use it at night because i am already using RetAsphere, but i do find it soothing if my skin has had a rough/stressful day (like if i have over exfoliated or something) and will apply it over the RetAsphere. i do think i will give it a try as a daily moisturizer once winter starts.

      (Posted on 7/1/13) Review by alex
    • This moisturizer is a breakthrough. It changes my skin overnight into soft, glowing skin. The cream itself is so luxurious feeling and I wake up to radiant skin. The signature packaging is one of my favorite things about the Kate Somerville product line. I can break out and this product did not cause me any breakouts.

      (Posted on 6/30/13) Review by Trish
    • The product is wonderful. My skin felt so much better and my skin tone was more even within two days. The only reason I didn't rate this 5 stars is due to the packaging. I had difficulty getting the lid off, the top outside portion of the lid separated from the inside and the inside container came out of the bottom exterior. Other than that, it's perfect!

      (Posted on 6/24/13) Review by Maureen
    • I received a sample of the Cyto Cell Dermal Energizing Treatment with an order. I forgot about it until I needed something because I was running low on my other product that I used.

      This product is comparable in price to some others that I've used and this is my product of choice! Well worth the money. I can't say enough about this product....amazing!! When I don't use it, I can see there is a difference in my skin. This treatment makes my skin look and feel refreshed, it also helps heal! Needless to say, my former must have products are no longer needed. THANKS FOR YOUR WONDERFUL PRODUCTS KATE!!

      (Posted on 6/5/13) Review by DANA
    • I have acne prone skin so I use all the products to combat acne, however once the acne clears you are still left with the unsightly red marks that take months to fade. This stuff helps speed up that process. I love it!

      (Posted on 6/3/13) Review by Natalie
    • I am 28 years old, and never had any real skin problems until I was about 24 or 25. I developed some mild acne that later progressed into adult cystic acne that I just couldn't seem to control. I had tried proactive, Murad, Clinique, and several other notable skin regimens, but nothing seemed to really help the problem. Everything was over drying, and then the moisturizer would cause me to break out. I happened to get this in a sample, and noticed results within a week. The problem wasn't just the breakouts; it was the scarring, uneven skin tone, and overproduction of oil that I couldn't seem to get control over. Then trying to incorporate anti-aging into that? I was using a hundred different products just trying to get all of my bases covered, and my problems just weren't getting any better...until THIS.

      I know the price on this is a little steep, but it's honestly worth it. The jar lasts FOREVER. AND even for someone with oily skin this doesn't irritate me. It's completely eliminated scarring, and evened out my skin tone. It allows me to get the right amount of moisture, but doesn't clog my pores. I never thought using a cream that wasn't oil-free would give me such great results. My friends constantly compliment me on my complexion now. I even took a picture with ZERO makeup on the other day, and it looked like I was wearing makeup! I couldn't believe how even my complexion was and what a great glow I had. I will be using this product for LIFE! Thank you Kate Somerville for SAVING my skin.

      (Posted on 5/23/13) Review by DanniCupcake
    • This is definitely a pricey product but I still really like it. It lasts a long time because you really do not need that much each time you use it. I am in my early 30's and am trying to keep my skin as healthy as possible. Have never done any type of botox or injections and hope to keep it that way!

      (Posted on 5/6/13) Review by Rachael
    • I was a little concerned about purchasing this product because of the high cost, but for me, it is definitely worth it. I have noticed that my fine lines and wrinkles are diminished, particularly, if I use this product in conjunction with DermalQuench Liquid Lift. I think I have tried every skin line there is, but nothing quite compares to Kate's products. I am very impressed. As a tip: If you happy to live near a Nordstrom Store, their professionals at the Kate Summerville counter are more than happy to try products on your skin to see how they work for you.

      (Posted on 4/23/13) Review by Rose Marie
    • I found this product as a sample at Nordstroms. Since the first time I tried it, my skin felt right. There are truly no words to describe the feeling. I was in awe and have been hooked on this product since them.

      (Posted on 3/22/13) Review by Hilda
    • I found this product thru in a sample, and I was hooked. I am extremely loyal to this product. I have dull (slightly dry) pale skin. This product gives me a glow that I was shocked. It is truly amazing...and whenever I run out, I panic! It's well worth every cent! and saving to use the dark circle cytocell treatment next!
      thank you Kate Somerville!

      (Posted on 3/19/13) Review by heather
    • I received this as a sample, and knew from the very first use that it was just what my face needed, and I couldn't be without it. When I woke up the following morning after that first use, my face felt just like velvet. It was a softness I have not felt before, but I hope I will always feel it forever, now!

      (Posted on 3/15/13) Review by Mary
    • I think I have found my skin's favorite product! I look forward to putting it on because it is so hydrating and the smell is very fresh and subtle. The bonus is the way my skin has responded... my pores appear smaller, my skin tone appears more even and glowing, and my fine lines appear to be smaller.

      (Posted on 3/3/13) Review by Amy
    • The CytoCell line is my favorite. You cannot go wrong here. I love this. My skin has become balanced using it. No more dry or oily skin. No more breakouts. I have noticed my skin is smoother and clearer...bottom line. Amazing!! Oh, and it smells very refreshing. I do wish it was less expensive; however, I do appreciate the occasional promotions.

      (Posted on 2/5/13) Review by Rebekah
    • I have been using this for a few months after buying it because I had used a sample. I am 50 years old with normal to dry skin. I do have some wrinkles on my forehead but this is definitely making them less noticeable. I have been using this with a day cream and night cream that I already had but can't wait to include the Kate products and see if I notice even more improvement. Great product!

      (Posted on 1/29/13) Review by Sheila
    • I use this wonderful product as my moisturizer, acne reducer, and skin smoother! It does it all! It is pricey but worth the splurge. Love it!

      (Posted on 1/29/13) Review by Christy
    • This product got me hooked on Kate's moisturizers. I love the way my skin looks and feels after using it, which has been 2 years now.

      (Posted on 1/29/13) Review by cheryl
    • At first, I was not sure this product had any effect, but then I noticed a negative difference if I did not use it for a few days. Therefore, I knew it did something positive, but I can't really describe it. CytoCell just made my skin look better. Then, after a Kate representative told me to use CytoCell as a serum before Deep Tissue, my skin really made a noticeable improvement - seriously. (I also use the Kate exfoliants, Hydrakate and Total Vitamin.)

      (Posted on 1/26/13) Review by A
    • I have heard so many good things about this product, it's performed miracles basically in helping to remove scars and really renew the skin. It basically gives you a fresh slate! I really loved it for myself too. I had a small size sample and will definitely b purchasing the full size. It lasts forever and will change you skin!

      (Posted on 1/9/13) Review by Cassie
    • I first received this as a sample packet and made it last for a week. My skin which is aging and extremely acne prone, was soft and smooth. I had just finished my third round of Accutane, the first being almost 30 years ago, and the dryness was immediately relieved with this product. Acne scars became softened and the overall appearance of my skin was much improved. I continued to use the product for about a year, but it is very pricey so now I use it for about 6 months on, then 6 months off.

      (Posted on 1/1/13) Review by TTT
    • I have been using the Cytocell cream for a little over a year now. I apply it at night after my cleanser. It leaves a very soft finish and my acne scarring has actually started to diminish over time. Not sure if that is supposed to happen, but it has had that effect on me. Doesn't clog my pores and has a nice light scent to it. Non fragrant like which I like... Highly recommend!!:

      (Posted on 11/29/12) Review by AshleyAliceArtistry

    • This product did not work for me. I felt my fine lines were much more pronounced.

      (Posted on 10/2/12) Review by Betty
    • The very best product I've ever used and I've used them all. Love, love, love it. Worth every penny! Never going without it!

      (Posted on 7/16/12) Review by Deborah
    • Excellent! Worth every penny! And you get more for the price.1.7oz.

      (Posted on 5/11/12) Review by Debra
    • this product plumps your also heals! if you have any scars or blemishes, this will target those areas and you will see healing awesome!!!

      (Posted on 3/24/12) Review by Lisa
    • I love this product! It delivers everything it promises! Worth every penny!

      (Posted on 12/28/11) Review by Deb
    • I obtained a sample of this with a Sephora order ages ago and fell in love. My skin was soooo soft after and felt tighter as well. I never, ever spend this much on one cream (Usually use Nourish and Oil free) but have found a way to keep using it as it makes my skin feel great! I no longer get oily during that time of month and I use this at night and put Nourish or the Oil-Free over the top for extra moisture.

      (Posted on 11/30/11) Review by coolmom3
    • I love how this cream hydrates ...and how kate's products deliver: firms, tones, my skins feels amazing, just like kate's products!!!

      (Posted on 8/22/11) Review by Lucy
    • I remember being in school when this product was announced a little over a year ago, there was a short video/trailer that went along with the announcement and I made all of my friends watch it. I know they thought I was crazy but I was really excited for this launch!!!!! The treatment/mosturizer is very dense and hydrates very well. I love the smell of this product and the fact that it is working to reduce signs of aging (my greatest fear is a wrinkle) is all that I need to know to feel safe in the fight of the aging process!!!!!

      (Posted on 8/17/11) Review by Dylan

Clincal Results

In a Consumer Use Study after 7 days*:

  • 87% of women reported that their skin felt significantly more even
  • 93% of women reported a significant reduction in roughness and dryness

* Results based on an independent Clinical Study.